![]() High Alert: Do not confuse Toprol-XL (metoprolol succinate) with Topamax (topiramate).Before administering intravenously, have second practitioner independently check original order and dose calculations. High Alert: IV vasoactive medications are inherently dangerous.Geri: Older adults may have ↑ sensitivity to beta blockers initial dose ↓ recommended.Pedi: Safety and effectiveness not established in children ![]() ![]() Lactation: Use while breastfeeding only if potential maternal benefit justifies potential risk to infant may result in bradycardia, constipation, diarrhea, and dry mouth/skin/eyes in infant, especially in mothers who are CYP2D6 poor metabolizers.OB: Use during pregnancy only if potential maternal benefit justifies potential fetal risk crosses the placenta and may cause fetal/neonatal bradycardia, hypotension, hypoglycemia, or respiratory depression.Untreated pheochromocytoma (initiate only after alpha blocker therapy started).Patients with a history of severe allergic reactions (intensity of reactions may be ↑). ![]()
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January 2023
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